Hemostasis Coagulation Practice Test

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Wiskott-Aldrich syndrome typically presents with which combination?

Thrombocytosis, giant platelets

Thrombocythemia, eczema

Thrombocytopenia, giant platelets

Thrombocytopenia, eczema

Wiskott-Aldrich syndrome presents with low platelets (thrombocytopenia) and small platelets along with eczema and immune dysfunction. The combination of thrombocytopenia and eczema is classic for this condition, reflecting both the bleeding tendency from the low platelet count and the skin/immune problems that accompany the syndrome. Giant platelets are not typical in WAS—the platelets are characteristically small—so options describing large platelets or high platelet counts do not fit. This is why the pattern of thrombocytopenia with eczema best matches Wiskott-Aldrich syndrome.

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